Nabumetone Side Effects

Nabumetone side effects can include nausea, constipation, and itching. There are also some serious side effects with nabumetone that can lead to potentially life-threatening complications. For example, since nabumetone can increase the risk of major or life-threatening bleeding, you should contact your healthcare provider immediately if you have a bloody nose or blood in the urine or stools while taking nabumetone.

 

Nabumetone Side Effects: An Introduction

As with any medicine, there are possible side effects with nabumetone (Relafen®); but not everyone who takes nabumetone will experience side effects. In fact, most people tolerate nabumetone well. When side effects do occur, in many cases they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
 
(The nabumetone side effects discussed below are not a complete list of side effects reported with this drug. Your healthcare provider can discuss a more complete list of side effects with you.)
 

Common Nabumetone Side Effects

Nabumetone has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. In these studies, side effects are always documented and compared to side effects that occur in a similar group of people not taking the medicine. Based on these studies, the most common nabumetone side effects include:
 
  • Diarrhea -- up to 14 percent
  • Heartburn or indigestion (dyspepsia) -- up to 13 percent
  • Stomach pain -- up to 12 percent.
     
Other side effects occurring in more than 3 percent of people included:
 
  • Constipation
  • Gas
  • Nausea
  • Unexplained bleeding
  • Dizziness
  • Dry mouth
  • Headache
  • Itching
  • Unexplained rash
  • Ringing in the ears (tinnitus)
  • Swelling.
     
(Nabumetone Side Effects Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;