An Introduction to Nabumetone Side Effects
As with any medicine, there are possible side effects with
nabumetone (
Relafen®); but not everyone who takes nabumetone will have problems. In fact, most people tolerate nabumetone well. When side effects do occur, in many cases they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
(The side effects discussed below are not a complete list of side effects reported with nabumetone. Your healthcare provider can discuss a more complete list of side effects with you.)
Serious Side Effects of Nabumetone
As with any drug, nabumetone has the potential to cause serious side effects.
The U.S. Food and Drug Administration (FDA) warns that people using
NSAIDs, including nabumetone, may have a higher risk of having a
heart attack or
stroke than those people who do not take NSAIDs; this warning does not apply to those who take aspirin. This risk may be higher in people who have been taking NSAIDs for a long time. These events can occur without any warning and can lead to loss of life.
Get emergency medical help by calling 911 or an ambulance as soon as possible if you experience any of the following symptoms:
- Chest pain
- Shortness of breath
- Weakness on one part of your body
- Slurred speech.
Other possible serious side effects include but are not limited to:
- Allergic reactions such as swelling of the face or body, blisters, unexplained skin rash, wheezing, or difficultly breathing
- Stomach or intestinal problems, including bleeding, ulcers, or a hole (known as a perforation)
- Liver damage, which can cause nausea, fatigue, yellowing of the skin or whites of the eyes, and excessive tiredness
- Kidney problems, including kidney failure
- Fluid retention or unexplained weight gain
- Congestive heart failure
- Sensation that the pill is stuck in your throat.
Because nabumetone can increase the risk of major or life-threatening bleeding, contact your healthcare provider immediately if you notice any unusual bleeding or have any of the following symptoms:
- Bloody nose
- Black, tarry stools
- Blood in the urine or stools
- Vomiting blood
- Red or purple spots on the skin.
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