More Instructions for Naproxen Sodium

Drug Interactions

Naproxen sodium can potentially interact with several medicines (see Naproxen Sodium Drug Interactions).

What Should I Tell My Healthcare Provider?

The U.S. Food and Drug Administration (FDA) warns that people using NSAIDs (other than aspirin), including naproxen sodium, may have a higher risk of developing a heart attack or stroke than those who do not take NSAIDs. This risk may be higher in people who have been taking NSAIDs for a long time. These events can occur without any warning and can lead to death. Tell your doctor if you have or ever had any of the following:
You should also talk to your healthcare provider prior to taking naproxen sodium if you have:
  • Asthma
  • Congestive heart failure
  • Liver disease or liver failure
  • Kidney disease or kidney failure
  • Bleeding problems or are taking medicine that decreases the blood's ability to clot
  • Diabetes
  • Stomach ulcers, stomach bleeding, or a history of either one
  • Any allergies to medicines, including sulfa drugs, aspirin, or other NSAID pain medicines.
Let your healthcare provider know if you:
  • Are pregnant or thinking about becoming pregnant (see Naproxen and Pregnancy)
  • Are breastfeeding
  • Drink alcohol frequently
  • Smoke
  • Are having or have recently had heart surgery.
Also, tell your healthcare provider about all other medicines that you may currently be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Naproxen Sodium Precautions and Warnings to learn more, including information on who should not take the drug.)
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