Naproxen Drug Interactions

When certain medicines (such as lithium or aspirin) are taken with naproxen, drug interactions may occur. Some interactions may cause serious side effects, such as an increased risk of bleeding, stomach ulcers, or increased levels of naproxen in the blood. Other medications that can potentially cause interactions include other NSAIDs, cholestyramine, and beta blockers.

Naproxen Interactions: An Overview

Naproxen (brand names include Aleve®, Naprosyn®, EC-Naprosyn®, Anaprox®, Anaprox® DS, and Naprelan®) can potentially interact with a number of medicines. Some of the medicines that may cause naproxen drug interactions include:
 
 
  • Angiotensin II receptor blockers (ARBs), such as:

 

 
 
 
  • Corticosteroids, including (but not limited to):
     
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 
 
 
 
 
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
 
 
 
Several herbal and nutritional supplements can also interact with naproxen and may increase the risk of bleeding. Examples of these include but are not limited to:
 
Top Foods to Fight Inflammation

Naproxen Drug Information

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