There are a number of medications that should not be taken with Orencia. If this rheumatoid arthritis medication is taken with "live" vaccinations, TNF inhibitors, or anakinra, drug interactions with Orencia could occur. As a result, you may experience an increased risk of developing an infection or other side effects.
Orencia® (abatacept) can potentially interact with a few other medications, particularly other medications that affect the immune system. Some of the medicines that may lead to drug interactions with Orencia include:
The following sections explain in detail the potentially negative interactions that can occur when Orencia is combined with any of the drugs listed above.