Pennsaid Side Effects

Although most people tolerate the medicine well, side effects are possible with Pennsaid. Some of the most commonly reported problems in clinical studies included dry skin at the application site and an itchy, red rash at the application site. Serious reactions are also possible; contact your healthcare provider immediately if you develop chest pain, slurred speech, or other potentially dangerous symptoms.

An Introduction to Pennsaid Side Effects

As with any medicine, side effects are possible with Pennsaid® (diclofenac sodium topical solution). However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Pennsaid. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Pennsaid

Pennsaid has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people using this drug were documented and compared to those that occurred in another group of people using a placebo solution (a solution with no active ingredients). This way, it is possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In these studies, the most common Pennsaid side effects included:
  • Dry skin at the application site -- in up to 32 percent of people
  • Contact dermatitis (an itchy, red skin reaction) at the application site -- up to 9 percent
  • Indigestion or heartburn -- up to 8 percent
  • Abdominal pain (stomach pain) -- up to 6 percent.
Other common side effects (occurring in 1 to 4 percent of people) included:
Top Foods to Fight Inflammation

Pennsaid Medication Information

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