Drug Interactions With Piroxicam

Drug interactions with piroxicam can increase the risk of stomach ulcers, kidney damage, and bleeding, as well as change the way your body metabolizes the medications. Lithium, warfarin, aspirin, and cyclosporine are a few of the drugs that piroxicam can potentially interact with. Before taking piroxicam, be sure to talk with your healthcare provider about any potential drug interactions that may apply to you.

 

Drug Interactions With Piroxicam: An Introduction

Piroxicam (Feldene®) can potentially interact with a number of medicines. Some of these Piroxicam drug interactions include:
 

 

Several herbal and nutritional supplements can also interact with piroxicam and may increase the risk of bleeding. Examples of these include, but are not limited to:
 
Warfarin (Coumadin, Jantoven)
If you are taking other blood thinners, such as warfarin, while taking piroxicam, your body may metabolize them differently than intended. You healthcare provider may choose to monitor your INR and prothrombin time more frequently and adjust accordingly. INR and prothrombin time are tests used to measure how well your blood is clotting.
(Drug Interactions With Piroxicam Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;