Drug Interactions With Piroxicam

Lithium, warfarin, aspirin, and cyclosporine are some of the drugs that can interact with piroxicam. Drug interactions can increase the risk of stomach ulcers, kidney damage, and bleeding, as well as change the way your body metabolizes the medications. Before taking piroxicam, talk with your healthcare provider about any interactions that may apply to you.

Piroxicam Drug

Piroxicam Interactions: An Overview

Piroxicam (Feldene^®) can potentially interact with a number of medicines. Some of the medications that may cause drug interactions with piroxicam include:

Warfarin (Coumadin^®, Jantoven^®)
Other nonsteroidal anti-inflammatory drugs (NSAIDs), such as:

Ibuprofen (Advil^®, Motrin^®)
Naproxen (Aleve^®, Anaprox^®, Naprosyn^®, Naprelan^®)
Diclofenac (Cataflam^®, Voltaren^®)
Indomethacin (Indocin^®)
Nabumetone (Relafen^®)
Oxaprozin (Daypro^®)
Celecoxib (Celebrex^®)
Etodolac (Lodine^®, Lodine^® XL)

Meloxicam (Mobic^®), and others

Aspirin
Lithium (Eskalith^®, Lithane^®, Lithonate^®, Lithotabs^®)
Diuretics, such as torsemide (Demadex^®), furosemide (Lasix^®), and hydrochlorothiazide
ACE inhibitors, such as:

Ramipril (Altace^®)

Methotrexate (Rheumatrex^®, Trexall^™)
Cyclosporine (Gengraf^®, Neoral^®, Sandimmune^®)
Corticosteroids, such as prednisone, hydrocortisone (Cortef^®), dexamethasone (Decadron^®, Dexone^®, Hexadrol^®), and many others.

Several herbal and nutritional supplements can also interact with piroxicam and may increase the risk of bleeding. Examples of these include but are not limited to:

Dong quai
Feverfew
Garlic
Ginger
Ginkgo biloba
Ginseng
St. John's wort
Fish oil supplements.

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(Drug Interactions With Piroxicam Continued: Page 2)