Can Piroxicam Cause Problems?

Side Effects

(The side effects listed below are NOT a complete list of possible side effects of piroxicam. Your healthcare provider can discuss a more complete list of side effects with you.)
 
As with any medicine, there are possible side effects with piroxicam. Not everyone who takes it will experience side effects, however. When people do develop side effects, in many cases they are minor, meaning that they require no treatment or are easily treated by a healthcare provider.
 
Common side effects of piroxicam include, but are not limited to:
 
  • Heartburn or indigestion (dyspepsia)
  • Swelling
  • Stomach pain
  • Diarrhea
  • Elevated liver enzymes
  • Gas
  • Unexplained bleeding
  • Ulcer in the stomach or intestines (peptic ulcer)
  • Anemia
  • Nausea
  • Dizziness
  • Headache
  • Tiredness or weakness
  • Unexplained rash
  • Itching
  • Ringing in the ears (tinnitus).
     
Less common but serious side effects include:
 
  • Cardiovascular problems, including a heart attack or stroke
  • Stomach or intestinal problems, including bleeding, ulcers, or a hole (known as a perforation)
  • Liver damage
  • Kidney problems, including kidney failure
  • Fluid retention
  • Congestive heart failure
  • Allergic reaction
  • Unexplained rash.
     
These possible side effects are shared with all NSAIDs and can lead to life-threatening complications or even loss of life.
 
(Click Side Effects of Piroxicam to learn about specific side effects of the drug, including potentially serious side effects to look out for.)
 
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