Side Effects of Piroxicam

Common Side Effects of Piroxicam

Piroxicam has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. In these studies, side effects are always documented and compared to side effects that occur in a similar group of people not taking the medicine. This way, it is possible to see what side effects occur, how often they occur, and how they compare to the group not taking the medicine.
 
Based on these studies, the most common piroxicam side effects include:
 
  • Heartburn or indigestion (dyspepsia)
  • Swelling
  • Stomach pain
  • Diarrhea
  • Elevated liver enzymes
  • Gas
  • Unexplained bleeding
  • Ulcer in the stomach or intestines (peptic ulcer)
  • Anemia
  • Nausea
  • Dizziness
  • Headache
  • Tiredness or weakness
  • Unexplained rash
  • Itching
  • Ringing in the ears (tinnitus).
     

Rare Piroxicam Side Effects

During clinical studies, some side effects occurred in less than 1 percent of people taking piroxicam. Because these side effects are so uncommon, it is difficult to tell whether they are because of the medication or something else. These side effects include but are not limited to:
 

Final Thoughts

You may experience some of the side effects of piroxicam listed in this article or none at all. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, make sure to let your healthcare provider know if you develop any side effects during treatment. Also, let your healthcare provider know if you develop something that "just does not seem right." While it may not be a piroxicam side effect, your healthcare provider will be able to diagnose and treat the problem.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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