Several drugs can interact with Simponi, including warfarin, cyclosporine, and the chickenpox vaccine. These interactions can increase your risk of problems such as infections. In the case of live vaccines, Simponi can make them less effective. To help ensure a safe treatment process, your healthcare provider may monitor you more closely and adjust your dosages, if necessary.
An Overview of Interactions With SimponiSimponi™ (golimumab) can potentially interact with a few other medications. Some of the drugs that may lead to interactions with Simponi include:
- Abatacept (Orencia®)
- Anakinra (Kineret®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- "Live" vaccinations, including:
- Theophylline (Uniphyl®, Theocron®, TheoCap®, Theo-24®, Elixophyllin®)
- Warfarin (Coumadin®, Jantoven®).
Simponi Drug Interactions ExplainedThe following sections explain in detail the potentially negative interactions that can occur when Simponi is combined with any of the drugs listed above.
Taking Simponi with abatacept can increase your risk of getting an infection. In general, these two medications should not be combined.