Simponi Uses

Simponi is approved to treat ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. This product belongs to a group of drugs called tumor necrosis factor (TNF) blockers. TNF-alpha is a naturally occurring chemical in the body that can contribute to various diseases by encouraging inflammation. When a person uses Simponi, this chemical is blocked -- as a result, this reduces inflammation and lessens a person's symptoms.

What Is Simponi Used For?

Simponi™ (golimumab) is a prescription medication licensed to treat certain inflammatory conditions that affect the joints or skin. Specific Simponi uses include the treatment of:

Using Simponi for Ankylosing Spondylitis

Ankylosing spondylitis is an autoimmune disease that causes painful arthritis of the spine. In people with this condition, the immune system begins functioning abnormally and starts attacking the spine. This results in pain and stiffness, especially in the lower back. Other ankylosing spondylitis symptoms include changes in vision and possibly problems in the heart, lungs, or digestive system.
Simponi is approved to treat active ankylosing spondylitis in adults.

Simponi Uses for Psoriatic Arthritis

Psoriatic arthritis is a form of joint inflammation in people with psoriasis. Not all people with psoriasis will develop it. Some psoriatic arthritis symptoms include painfully inflamed joints and changes in the eyes and the fingernails.
Simponi is used to treat psoriatic arthritis in adults, either alone or in combination with methotrexate.

Simponi Uses for Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune disease. This means that for some reason the immune system mistakes a person's own cells as invaders and attacks them, causing damage. Similar to other autoimmune diseases, scientists still do not know the cause or causes of rheumatoid arthritis.
There are many rheumatoid arthritis symptoms, including chronic pain along with tender, warm, and swollen joints. Simponi is approved to treat moderate-to-severe active rheumatoid arthritis in adults. When used to treat rheumatoid arthritis, Simponi is approved only for use with methotrexate.
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Simponi Medication Information

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