Sulindac Dosing

When treating arthritis symptoms with sulindac, dosage recommendations typically start at 150 mg, twice a day. However, your healthcare provider may increase your dosage if pain associated with arthritis does not subside after several weeks. For acute pain relief or the relief of symptoms related to gout, dosing guidelines call for 200 mg, twice a day.

 

An Introduction to Sulindac Dosages

The dose of sulindac (Clinoril®) that your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • The medical condition you are being treated for
  • Other medical conditions you may have
  • Other medications you may be currently taking.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Acute Pain and Gout

For acute pain relief or the relief of gout symptoms, the usual dose of sulindac is 200 mg, twice a day. It typically takes about 7 to 14 days for the full effects to be felt for acute pain. Seven days is usually adequate for gout treatment.
 

Rheumatoid Arthritis, Osteoarthritis, and Ankylosing Spondylitis

The recommended starting dosage of sulindac for most people with rheumatoid arthritis, osteoarthritis, or ankylosing spondylitis is 150 mg, twice a day.
 
After several weeks, your healthcare provider may choose to increase your dose if pain is still present. If pain still does not improve, your healthcare provider may recommend other options for pain relief.
 
If taking sulindac to help relieve arthritis symptoms, such as joint inflammation, it may take one to two weeks for the full effects to be felt. However, sulindac typically relieves pain to some degree in about one hour.
 
(Sulindac Dosing Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;