Synvisc Adverse Effects

Synvisc® (hylan G-F 20) is an osteoarthritis treatment specifically approved for people with arthritis of the knees who have not received adequate pain relief from medications. Although most people tend to respond well to Synvisc, adverse effects are possible.
 
During clinical trials, the most common side effect of Synvisc was knee pain or swelling, which occurred in up to 7.2 percent of people. In most cases, this problem is mild and can be treated with pain relievers (if treatment is even necessary). More severe cases may require the joint to be drained or steroid injections into the joint. Because knee pain and swelling may be signs of serious problems (such as an infection), be sure to report such problems to your healthcare provider right away.
 
Other possible adverse effects with Synvisc include:
 
  • Muscle pain or muscle cramps
  • Flushing of the face
  • A rapid heart rate (tachycardia)
  • Nausea
  • Dizziness
  • Fever and/or chills
  • Headaches
  • Unusual sensations on the skin, such as tingling or pricking
  • Low blood platelets
  • Ankle swelling
  • Hemorrhoids
  • Lower back pain.
     
(Click Synvisc Side Effects to learn about other possible adverse effects and to find out which ones may require medical attention.)
 
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