Tylenol Drug Interactions

Interactions With Tylenol Explained

The following sections explain in detail the potentially negative interactions that can occur when Tylenol is combined with any of the drugs listed above.
 
Alcohol
Alcohol can affect the way your body handles Tylenol, making it more toxic. If you drink more than three alcoholic beverages a day, talk to your healthcare provider before taking Tylenol (see Tylenol and Alcohol).
 
Barbiturates
Barbiturates can affect the way your body handles Tylenol, making both drugs less effective and more toxic. This is most important for people who take high doses of Tylenol on a regular basis. Talk to your healthcare provider about combining these two medications.
 
Carbamazepine (Carbatrol, Epitol, Equetro, Tegretol)
Carbamazepine can affect the way your body handles Tylenol, making both drugs less effective and more toxic. This is most important for people who take high doses of Tylenol on a regular basis. Talk to your healthcare provider about using these drugs together.
 
Cholestyramine (Prevalite, Questran)
Cholestyramine can bind to Tylenol and prevent it from being absorbed into your bloodstream. Make sure to separate these products by at least one hour.
 
Codeine and Acetaminophen Products
In general, you should avoid Tylenol if you are taking codeine and acetaminophen products, as you may inadvertently take too much acetaminophen (the active ingredient of Tylenol). Be very careful to monitor the amount of acetaminophen you take each day, and do not exceed 4000 mg per day (for adults).
 
Hydrocodone and Acetaminophen Products
In general, you should avoid Tylenol if you are taking hydrocodone and acetaminophen products, as you may inadvertently take too much acetaminophen (the active ingredient of Tylenol). Be very careful to monitor the amount of acetaminophen you take each day, and do not exceed 4000 mg per day (for adults).
Alternative Therapies for Pain Management

Tylenol Medication Information

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