Uloric Drug Interactions

When Uloric is taken with chemotherapy medications, mercaptopurine, theophylline, or a number of other medications, drug interactions could occur. Drug interactions such as these may alter the amount of the medications in your blood, increasing your risk of potentially serious side effects. To reduce your chances of drug interactions with Uloric, make sure to tell your healthcare provider about any other medicines you are currently taking.

Uloric Medication Information

Interactions With Uloric: An Overview

Uloric^® (febuxostat) can potentially interact with a number of other medications. Some of the medicines that may lead to Uloric drug interactions include (but are not limited to):

Azathioprine (Azasan^®, Imuran^®)
Chemotherapy medications
Mercaptopurine (Purinethol^®)
Theophylline (Uniphyl^®, Theocron^®, TheoCap^®, Theo-24^®, Elixophyllin^®).

Uloric Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Uloric is combined with any of the drugs listed above.

Azathioprine

Uloric could substantially increase the level of azathioprine in your blood, increasing the risk of side effects of azathioprine. These medications should not be taken together.

Chemotherapy

It is not known if it is safe to take Uloric while you are undergoing chemotherapy treatments. It is possible that serious problems could occur. If your healthcare provider recommends that you take Uloric while receiving chemotherapy, you may need to be monitored more closely.

Mercaptopurine

Uloric could substantially increase the level of mercaptopurine in your blood, increasing the risk of side effects of mercaptopurine. These medications should not be taken together.

(Uloric Drug Interactions Continued: Page 2)