Xarelto Drug Interactions

Tell your healthcare provider about any medications, herbal supplements, or vitamins you are taking before starting treatment with Xarelto. Drug interactions may occur when it is combined with certain products that affect liver enzymes and medicines that increase the risk for bleeding. Some of these negative reactions may decrease the effectiveness of Xarelto or increase your risk for serious side effects.

An Overview of Interactions With Xarelto

Xarelto® (rivaroxaban) may react with a number of other medications. Some of the drugs that can lead to interactions with Xarelto include but are not limited to:
  • CYP 3A4 inducer medications, such as:
  • CYP 3A4 inhibitor medications, such as:
  • Medications that increase the risk of bleeding, such as:
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
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Xarelto Drug Information

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