Xeljanz Uses

How Does It Work?

Xeljanz works by blocking enzymes in the body known as janus-associated kinases (JAKs). JAK enzymes help regulate immune cell function. Xeljanz inhibits JAK enzymes; however, it is not entirely clear how this action helps to improve symptoms of rheumatoid arthritis.  
 

Is It Safe for Children to Use Xeljanz?

Xeljanz has not been adequately studied in children and is not approved for use in this age group. Talk to your child's healthcare provider about the risks and benefits of using this medication in children.
 

Can Older Adults Use It?

In clinical studies, older adults given Xeljanz had a high risk for infections, compared with younger age groups. This medication can be used in older adults, although a careful assessment of the risks versus benefits is particularly important.
 

Off-Label Xeljanz Uses

On occasion, your healthcare provider may recommend this medicine for treating something other than the condition discussed in this article. This is called an "off-label" use. Xeljanz has been studied for a variety of other conditions, such as psoriasis, transplant rejection, and other immunologic diseases. It may someday be approved for such uses; however, at this time, these would be off-label uses.
 
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Xeljanz Medication Information

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