Zydone and Breastfeeding

In most cases, Zydone should not be taken while breastfeeding. Zydone contains a narcotic, which could cause significant problems in a nursing infant if it passes through breast milk (this is currently unknown). The acetaminophen component does pass through breast milk, but should not cause problems. If your healthcare provider recommends Zydone while breastfeeding, you may have to pump the milk and throw it away.

Can I Take Zydone While Breastfeeding?

Zydone® (hydrocodone/APAP) contains a narcotic medication. The manufacturer does not recommend that breastfeeding women take this medication, because it is not known if this narcotic passes through breast milk. If you are breastfeeding or are thinking about breastfeeding, talk with your healthcare provider before taking Zydone.
 

Zydone and Breastfeeding: What Are the Risks?

The acetaminophen (Tylenol®) component of Zydone does pass through breast milk, but it is not likely to cause problems (see Tylenol and Breastfeeding). Surprisingly, no studies have been done to see if the narcotic component of Zydone (hydrocodone) also passes through breast milk in women. As a narcotic, hydrocodone could cause significant problems for a nursing infant.
 

Talking With Your Healthcare Provider About Zydone and Breastfeeding

You should talk with your healthcare provider about Zydone and breastfeeding. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision about Zydone and breastfeeding that is right for you. In some cases, it may be possible to temporarily stop breastfeeding while taking Zydone. "Pumping and dumping" (pumping breast milk and discarding it) can be useful if a breastfeeding woman needs to take Zydone temporarily, such as after a surgery.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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